Heart-brain interactions in perseverative cognition: From experimental studies to clinical interventions
In my seminar, I will review a series of studies conducted in different settings (laboratory, fMRI, daily life), populations (healthy, major depression, generalized anxiety), location (United States, Europe), and age groups (children, adults) that consistently replicated the existence of a nexus between cognitive and autonomic inflexibility when examining the mind wandering – perseverative cognition continuum. More recent studies on the possibility to influence cognitive control by experimentally manipulating cortical excitability via non-invasive brain stimulation techniques will be presented, with important implications for the prevention and timely treatment of stress-related disorders
Sapienza University of Rome, Department of Psychology
Dysrégulation émotionnelle et irritabilité à l’enfance, et comportements suicidaires à l’adolescence et chez le jeune adulte.
Présentation des déterminants et stratégies de prévention
Suicidal ideation and suicide attempt (suicidality) are common in adolescence and a public health concern. Childhood depression is a key risk factor for later suicidality and often co-occurs with irritability. No study to date has examined the joint association of depressive mood and irritability during childhood with later suicidality. Childrenwithhighirritabilityanddepressive/anxiousmood and, to a lesser extent, with moderate irritability only had a higher suicidal risk during adolescence compared with children with low symptom levels. Early manifestation of chronic irritability during childhood, especially when combined with depressive/anxious mood, maybe associated with an elevated risk for adolescent suicidality. The putatively causal role of irritability should be investigated.